CBD Knowledge Base
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CBD (short for cannabidiol) is a non-intoxicating member of the phytocannabinoid family of chemical compounds that can be derived from the cannabis plant. All of the products made at Knockout CBD are hemp-derived.
Cannabidiol—CBD—is a cannabis compound that has significant medical benefits, but does not make people feel “stoned” and can actually counteract the psychoactivity of THC. The fact that CBD-rich cannabis is non-psychoactive or less psychoactive than THC-dominant strains makes it an appealing option for patients looking for relief from inflammation, pain, anxiety, psychosis, seizures, spasms, and other conditions without disconcerting feelings of lethargy or dysphoria.
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The endocannabinoid system (ECS) is a biologicalsystem composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the mammalian central nervous system (including the brain)
The Endocannabinoid System (ECS) is a recently discovered group of endogenous cannabinoid receptors found throughout the body.
The endocannabinoid receptors that make up the ECS are located in our Central Nervous System (CNS), Peripheral Nervous System (PNS), and Immune System. Our CNS includes our brain and spinal cord, while the PNS acts as a communication network linking our CNS to the rest of our body. Our brains contain the heaviest concentration of cannabinoid receptors, but there’s no shortage of them in our organs, tissues, glands, and more. The saturation of ECS receptors throughout our body is part of why CBD has so many uses and is so effective.
Cannabidiol, or CBD for short, naturally occurs within the tiny hairlike structures known as trichomes that grow on hemp and cannabis. The first cannabinoid molecule to be discovered in 1940, researchers have been studying CBD’s numerous health benefits ever since. CBD has been shown to promote healthy sleep, relieve occasional joint pain, speed athletic recovery, enhance relaxation, improve mood, reduce stress and frustration, alleviate occasional nausea, and support immune system health.
Cannabidiol exists in two states, CBD and CBD-a. Both are being studied to discover their individual effects on the body. CBD-a, which grows directly on hemp and cannabis, shows a great potential for different types of treatment. However, its effects haven’t been researched as extensively as CBD. When CBD-a is heated to 248°F, it loses its acid chain in a process called decarboxylation (also referred to as “activation”) and becomes CBD. All our products go through this process. CBD has been well studied and has a more pronounced effect than CBD-a due to more efficiently binding to the body’s Cannabidiol receptors.
An organic product, CBD is a safer, natural alternative to synthetic options with little to no side effects. In hemp’s multi-thousand-year history, there has never been a recorded fatality. While CBD has been shown to be non-toxic even at extreme doses, you should consult your doctor if you plan on taking more than 300mg in a 24 hour period.
Cannabinoids are a group of chemical compounds that are found in–but not exclusive to– cannabis. You can derive phytocannabinoids from pine needles and hops. Our body makes cannabinoids called endocannabinoids and act within the endocannabinoid system. At least 100 cannabinoids have been isolated from cannabis, but the most commonly recognized ones are cannabidiol (CBD), cannabinol (CBN), cannabigerol (CBG) and tetrahydrocannabinol (THC).
No. There are over 100 known cannabinoids, each with their own effect on the body. Though THC and CBD have similar chemical composition, their atoms are arranged differently. Because of the way THC is arranged molecularly, it is the perfect compound for interaction with Cannaboid 1 (CB1) receptors. This connection is the one that provides an intoxicating effect to the brain. CBD, however, is not a good connector to CB1. Instead, CBD connects with CB2 receptor. This produces a completely different effect on the body.
Tetrahydrocannabinol (THC) and cannabidiol (CBD) are the two primary cannabinoids that occur naturally in the Cannabis sativa plant, most commonly known as cannabis.
Both of these substances interact with the cannabinoid receptors found in the human body and brain, but they differed dramatically in their effects.
CBD is non-psychoactive which means that it will not get the user high. Because of this trait, CBD appears more frequently than THC in dietary and natural supplements.
Hemp products that contain CBD are currently and successfully brought to market in all 50 states and over 40 countries by many businesses. We encourage users to always check with your local government, police department, or customs office for the most up to date information regarding the legality of CBD in your area before purchase. This answer should not be considered legal advice, so we strongly recommend that you check with your own local administration to ensure that you are happy with the level of legality of consuming these products before you buy them.
There is no simple answer. What may be ideal for one person might not be sufficient for others. Your serving size will be dependent on your body weight, individual body chemistry and concentration of the CBD product you’re consuming.
With that being said, a good rule of thumb to determine your proper CBD dosage is to take 1–6MG of CBD for every 10 pounds of body weight based on the individual’s level of pain. For example, 20MG-33MG would be a great starting dosage for a 200 lb patient, while 15MG-25MG would be best for another who weighs 150 lb.
We recommend using a small amount of CBD to start and adjusting as needed.